In order to understand the rationality of the structural design for one hydropower underground house, based on reasonable selection of loading method for generator pier, and appropriate dealing with volute casing and draft tube water pressure. Take a typical underground house of anlagensektion to build the three-dimensional finite element model, and spectrum method was applied to analyze underground powerhouse anti-seismic characteristic. The seismic response characteristic of powerhouse just under seismic action and static load of normal operation jointly are investigated. The anti-seismic safety property of powerhouse is evaluated. It provides scientific basis for powerhouse dynamic design and operation control that station project.