Wuhan Economic & Technological Development Zone (WEDZ) is situated to Zhuankou area, Wuhan. WEDZ is a national level development zone approved by the State Council of P.R.C. in April 1993. With nearly 20 years development history, WEDZ has grown into an important engine in economic development of Wuhan City. Meanwhile, atmospheric environment quality has become more and more worse, and paid on more and more attention. Great importance is attached to the identification of the sources of ambient particulates. The purpose of this study was to identify and estimate the contribution of major sources to atmospheric total suspended particulate (TSP) matter in Zhuankou area, Wuhan. In the study, the technique of factor analysis (FA) was employed to identify and quantify the major sources of atmospheric pollutant in Zhuankou area, Wuhan. The results indicate that the major sources of atmospheric pollutant in Zhuankou area are mainly construction and soil fugitive dust, coal-firing and motor vehicle.