Earthquake occurred on May 12, 2008 in Wenchuan, Sichuan Province, China, with magnitude of 8.0 and epicenter intensity of VI. Chencun hydropower station in southern Anhui Province has been shocked strongly during Wenchuan Earthquake, which stations 1,500 km away from Wenchuan. Tectonic stress caused by strong earthquakes inevitably led to the changes of stress state, groundwater level and pore pressure in the dam foundation. Seepage water level observation of the dam foundation had been encrypted immediately. According to the experimental data, it was conformed that significant effects were displayed on the dam foundation seepage because of Wenchuan earthquake, shunhe fault near dam sites was the main effect zone of earthquake tectonic stress, the downrange of groundwater depth was self-evident. As the existence of acrylamide curtain, swelling-shrinkage property of the acrylamide gel restricted the change of groundwater level and rock stress state in the dam foundation caused by seismic tectonic stress; the groundwater level behind the acrylamide curtain had a small decline, and recovering quickly.