Comparative analyses of twenty-eight finite element structures with filler walls were established to study dynamic characteristics of RC frame structures under seismic waves. The results of these analyses show that filler walls have little influence on vibration modes of the structure. But as a result of soft storey in the bottom of building caused by reduction of the filler walls, vibration modes have a great influence. As the stiffness of filler wall decrease, the stiffness of soft storey decrease shapely, vibration mode curve becomes much smoother. Considering the filler wall has influence on the vibration periods of framework, the reduction factor of 0.7 should be taken. The influence of filler wall to the value of lateral drift and storey displacement angle of frame can not be ignored. The main effect factors to the dynamic characteristics of framework are included quantity, location, material of the fill wall and the selection of seismic waves.