In order to model the elasto-plastic behavior of steel-concrete beams in high-rise buildings correctly and conveniently, plastic hinge method is used. Based on experimental and theoretical research on composite beams, the trilinear moment-curvature skeleton curve of steel-concrete composite beams is amended by numerical simulation and theoretical analysis. And the 4 poly-line moment-curvature skeleton curve model is suggested for elasto-plastic analysis of steel-concrete composite beams. The elastic-plastic model is then used for real composite beams under monotonic load experimental analysis to verify its precision. The suggested model can lay a foundation for the dynamic analysis under strong earthquake for the globe steel-concrete composite structures.