Paper Title:
Application of ICA-CMAC in the Prediction of Human Hepatic Clearance
  Abstract

In this paper, a novel improved Credit Assigned CMAC (ICA-CMAC) is designed based on the concept of credit to enhance the performance of the traditional CMAC. Then ICA-CMAC is used to predict the human hepatic clearance according to in-vitro data of drugs. The experiment results show that the prediction by ICA-CMAC is faster and more accurate and can be thought as a new and effective way for drug metabolism prediction.

  Info
Periodical
Advanced Materials Research (Volumes 268-270)
Edited by
Feng Xiong
Pages
1759-1762
DOI
10.4028/www.scientific.net/AMR.268-270.1759
Citation
Y. Q. Ge, X. P. Luo, Q. M. Mao, "Application of ICA-CMAC in the Prediction of Human Hepatic Clearance", Advanced Materials Research, Vols. 268-270, pp. 1759-1762, 2011
Online since
July 2011
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Price
$32.00
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