Training applied talent is the goal of current college. Several common experimental teaching methods, such as 1 × N Class -Team Teaching Model, N × N Class-Team Teaching Model, N × N Teacher-Team Teaching Model, are analyzed and compared. These experimental teaching methods have some disadvantages, which are that the ratio of teacher-student is small, or teacher professional expertise is not conducive to student’s comprehensive knowledge. A new experimental practice teaching model is given, which is Double Teams Model of Teachers and Students (DTMTS) experimental practice teaching model. This model can be used in course practice training, students’ research training and academic competition training. The implementation process of this model are teachers team building, students team building, to carry out experimental method of teaching practice, experimental practice teaching organization, the team teaching process management, strengthen the hardware platform construction of experimental practice. Its implementation can improve student’s participation in practice and innovation ability.