The major of advanced textile mechanical design and automation is a characteristic profession of School of Mechanical Engineering of Tianjin Polytechnic University. Since its establishment in 1978, it has gone through the course of near 30 years ，and has trained a large number of talented people for our country. In the new historical conditions, how to exert the professional advantages of cultivating innovative talents has become a hot topic. This paper analyzes the disadvantages that the college students who is trained by the closed education of the institutions of higher learning in the recent years can not meet the real requirements of the enterprises to the innovative talents ,and it is difficult that the college teachers and students conduct practical activities in the enterprises, proposes the establishment of " the Advanced Textile Mechanical and Electromechanical Center of Research and Development " that is the link of the school-enterprise cooperation and training innovative talents. It truly sets up a win-win mechanism between the school and enterprises and solves the above disadvantages. Through several years’ practice, after going into the enterprises the graduates can become skilled quickly and have strong practical ability and innovative design capability, and they are widely acclaimed by the enterprises.