The laser welding of Aluminum-Lithium alloy (Al-Li) alloy were conducted to investigate the weld porosity features in this paper. The results show that there are two kinds of weld porosity existing for laser welding Aluminum-Lithium alloy sheet. They are can be divided into metallurgical porosity and unstable keyhole porosity according to their different reason causing them. The mechanism of unstable keyhole porosity occurring was discussed according to the results of YAG laser welding processing. The methods how to reduce weld porosity for laser welding of Aluminum-Lithium alloy was also described.