Multi-target grey situation decision-making can make complex decision problems clear and improve the accuracy of decision. In this paper, it is used to rank the cleaning performance of cleaning cloths for LCD Display Panel. Ten representative cleaning cloths made of Polyester/ Polyamide composite microfiber are chosen. Evaluation indices which affect clean result are extracted and measured. The cleaning effects are then evaluated by both multi-target grey situation decision-making and actual performance appraisal, which show similar results.