In this study, the polyester fiber (PET) and absorbent cotton (AC) blend was needle-bonded to make the nonwoven PET/AC composite wound dressing matrix fabrics. The combined advantages of mechanical strength due to PET and water absorption due to AC make the composite nonwoven an attracting wound dressing matrix fabric. We examined physical features, such as mechanical properties, air permeability, softness, water imbibition, and water absorption rate, of the nonwovens made of different blending ratios of PET and AC. We found that while the strength and air permeability were slightly reduced at blending ratio of 80:20, the water imbibition increased about 1.6 cm for the same nonwoven. The results suggested that the optimal blending ratio for the nonwoven to be used as a wound dressing matrix is 80:20.