The principle of inking system in sheet-feed printing press is introduced. Some tests on ink thickness are performed and the experiment results shows that in the traditional press, some inherent defects cause serious quality problems. The application of shaft-less drive technology to printing press is introduced and the drive principle of inking rollers of printing press and is explained. Synchronization control method of rollers is put forward, and the shaft-less technology is applied to the inking roller. Control system of shaft-less roller press is constructed for four color printing. Mechanical zero and electrical zero can be reset and corrected. Slight asynchrony is allowed between inking rollers and cylinders for normal printing, and the speed difference between them can eliminate a kind of printing troublesome of ghosting when needed. Analysis shows that with this technology, the functions of press are extended. Furthermore, the results of calculation indicated that when printing the special products, the make-ready time for inking is shorten about 50% and the power consumption is decreased about 19.8 to 21.5%, so the efficiency of machine can be increased by a big margin and the power cost can be cut down obviously.