The fibrous materials made from collagen have some shortcomings, such as its mechanical property, water-resistant and thermal-stability. So the mixture is produced by blending collagen with chitosan at different mass ratio. Theirs mechanical, water-resistant and thermal-stability properties of these blending mixtures are characterized by FT-IR, DSC etc analyzing methods. These results indicate that the properties are improved great. Furthermore it obtains that the optimal ratio of collagen to chitosan is about 20:80.