Paper Title:
Fluorescent DNA Biosensors on Silica Microspheres
  Abstract

A novel DNA biosensor system on silica microspheres as solid carriers which based on the fluorescence resonance energy transfer (FRET) was presented in this work when CdTe quantum dots (QDs) were as energy donors and Au nanoparticles (AuNPs) were as energy accepters. Compared with the fluorescent intensity of CdTe QDs, the fluorescent intensity of DNA biosensors decreased extremely, which indicated that the FRET occurred between CdTe QDs and AuNPs. The biosensor system would have a certain degree recovery of fluorescence when the complementary single stranded DNA was introduced into this system. The DNA detection results indicated that this novel fluorescent DNA probe system could recognize the existence of complementary target DNA or not.

  Info
Periodical
Advanced Materials Research (Volumes 301-303)
Chapter
Chapter 1: Material Science and Technology
Edited by
Riza Esa and Yanwen Wu
Pages
195-200
DOI
10.4028/www.scientific.net/AMR.301-303.195
Citation
X. M. Ma, J. M. Zhang, Z. Dai, X. Y. Chen, X. Q. Wang, Q. Y. Zhang, "Fluorescent DNA Biosensors on Silica Microspheres", Advanced Materials Research, Vols. 301-303, pp. 195-200, 2011
Online since
July 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Kie Jin Lee, Arsen Babajayan, Song Hui Kim
Abstract:A near-field scanning microwave microscope (NSMM) is used to study the physical properties of DNA strands with a specific sequence and image...
1040
Authors: Xi Xi Huang, Zhong Cao, Yong Le Liu, Yi Min Dai, Ju Lan Zeng, Rong Hua Yang, Hiroyuki Takei
Abstract:An novel optical nano biosensor based on gold capped nano-particles for detecting binding events between ligands and receptor molecules as...
1554
Authors: Li Yan Zhao, Yan Fei Tian, Jiao Yun Xia, Jing Lin He, Ling Zhang, Zhong Cao
Abstract:A novel optical biosensor with gold surface bound silver nanoparticles has been constructed for detection of oncogene of c-Myc tagged DNA...
2935
Authors: Fu Tao Hu, Yuan Zao Wu, Yu Ting Cao, Ning Gan
Chapter 2: Inorganic Nonmetallic Materials
Abstract:A novel and sensitive electrochemical enzyme-linked immunosorbent assay (ELISA) system of Hydroquinones (HQ)- peroxide hydantoin (CP)...
200
Authors: Li Bo Nie, Hao Chang, Zhu Chen, Quan Guo He
Chapter 19: Biological Information Technology
Abstract:As the substrates of biosensor or biomicroarray, silicon, silica and gold matrixes are usually used as the surfaces of bio-recognition. In...
2991