In the present work, the MCF model for semisolid metal slurries (SSMS) is applied to investigate the thixotropy of the Al-6.5wt%Si alloy under cyclic shear deformation. The study shows that the semisolid Al-6.5wt%Si alloy has the behavior of thixotropy. The area of the hysteresis loop increases with decreasing the up-time, the initial shear rate and increasing resting time, solid volume fraction and maximum shear rate, respectively. These results have qualitative agreement with the experimental data. The origin of the hysteresis loop is atrributed to the difference between the deagglomeration rate and the agglomeration rate.