Paper Title:
Grafting Sulfoammonium Zwitterionic Brushes onto Polycarbonateurethane Surface to Improve Hemocompatibility
  Abstract

Poly(3-dimethyl(methacryloyloxyethyl)ammonium propane sulfonate) (poly(DMAPS)) zwitterionic brushes were grafted onto the polycarbonateurethane (PCU) surface to improve its hydrophilicity and hemocompatibility by Ultraviolet (UV) polymerization. Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS) and water contact angle were used to characterize the chemical and physical properties of the modified PCU surface. DMAPS-grafted PCU films showed significantly high hydrophilicity owing to the high hydrophilic poly(DMAPS) zwitterionic brushes. The cytotoxicity tests revealed the sulfoammonium zwitterionic brushes modified PCU film had good cytocompatibility. In addition, the hemocompatibility of the modified PCU films was evaluated by hemolytic tests and platelet adhesion tests. The PCU films modified with zwitterionic brushes had a lower hemolytic index, showed effective resistance to platelet adhesion. Due to the fact that sulfoammonium zwitterionic brushes can improve the hemocompatibility of the PCU surface, this gives rise to its potential application as blood-contacting materials or devices.

  Info
Periodical
Advanced Materials Research (Volumes 306-307)
Edited by
Shiquan Liu and Min Zuo
Pages
1631-1634
DOI
10.4028/www.scientific.net/AMR.306-307.1631
Citation
Y. K. Feng, D. Z. Yang, H. Y. Zhao, J. T. Guo, Q. L. Chen, J. S. Liu, "Grafting Sulfoammonium Zwitterionic Brushes onto Polycarbonateurethane Surface to Improve Hemocompatibility", Advanced Materials Research, Vols. 306-307, pp. 1631-1634, 2011
Online since
August 2011
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Price
$32.00
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