In this study, surface oxygen diffusion-hardened treatment for TC4 titanium alloy was carried out to enhance the wear and corrosion resistance. The surface oxygen diffusion-hardened treatment was performed in an electrical resistance furnace under atmosphere. Characterization of modified surface layers was made by means of microscopic examinations, microhardness measurements and X-ray diffraction (XRD) analysis. The wear resistance of both treated and untreated samples was evaluated. The accelerated corrosion tests in HCl solution was used to determine the corrosion resistance. The corrosion and wear resistant surface layers were obtained after treatment. The surface layers mainly consisted of rutile TiO2. A significant increment in surface hardness was achieved due to the formation of an oxygen diffusion zone. Corrosion and wear resistant surface on TC4 were obtained after the formation of diffusion zone.