Dynamic performance is one of the most important factors in the product’s life. Transmission housing is one of the important components in vehicle, which has direct influence on the vehicle’s powertrain performance. Dynamic topology optimization can improve the product’s performance. The dynamic topology model is built, in which the density of elements are the design variables, the displacement of frequency response and volume are the constraints, and the objective is to maximize the first natural frequency of the housing. According to the result of optimization, the CAD model of housing is rebuilt and the finite element analysis of the new housing is done.The results show that both the static and dynamic performance are improved besides the mass reduction, namely, dynamic topology optimization can significantly improve the product’s performance.