The effect of δ phase content on the hot deformation behavior of alloy IN718 has been investigated using isothermal compression tests. The results indicated that the δ phase has a significant effect on the deformation behavior of alloy IN718 during hot working. After the peak stress, the decreasing speed of the stress raises as the increase in the δ phase content. The deformation activation energy for alloy IN718 increases with the raise of the δ phase content. And the peak strain for the alloy decreases with the increase of the δ phase content, which indicates that the δ phase can stimulate the occurrence of dynamic recrystallization during hot working.