Based on the startup dynamics model axial flow blood pump system driven by large gap magnetic force, a method that realized optimal control in the blood pump acceleration by using VB programming was brought forward. In this method, Runge-Kutta algorithm was used to solve and analysis the model and the result that speed, flow and net head etc. time-domain curves were obtained; further more, suitable stable points in the speed curve could be found by setting threshold, and finally Hermite interpolation was used to discrete speed curve in conditions to get time constant and steps etc. speed control parameter. Relative to the old method for the speed control of blood pump, it is more accurate and controllability condition.