Paper Title:
Application of Amniotic Extracellular Matrix Nerve Conduit with Biological Material in the Peripheral Nerve Defect In Vivo
  Abstract

Objective: To evaluate the peripheral nerve regeneration using a nerve conduit of amniotic extracellular matrix (AECM). Methods: 5 mm gap in the rabbit facial nerve was repaired with AECM conduit or with a silica gel conduit. After 7 days, 1 month and 3 months, the medullated nerve fibers and neural conductive velocity were determined. Results: On the 7th day, no neural regeneration was observed. But the neoformative neural fibers across AECM and silica gel were seen in the following 3 months, while the number and conductive velocity of medullated nerve fibers varied significantly at the different time points. Conclusion: AECM could repair the peripheral nerve defect.

  Info
Periodical
Chapter
Chapter 1: Material Engineering and its Application
Edited by
Helen Zhang and David Jin
Pages
173-176
DOI
10.4028/www.scientific.net/AMR.322.173
Citation
Z. Gao, X. T. Luo, N. S. Li, W. Deng, S. M. Li, "Application of Amniotic Extracellular Matrix Nerve Conduit with Biological Material in the Peripheral Nerve Defect In Vivo", Advanced Materials Research, Vol. 322, pp. 173-176, 2011
Online since
August 2011
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Price
$32.00
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Chapter 1: Material Engineering and its Application
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