As an important content of engineering project management, information integrated management system is a public service platform of the whole system integrate management. In some way, the engineering project management is equal to project information management. Under the theory of information integration, this paper analysis the important role of the owner in the information integrated management, and puts forward the large-scale chemical engineering project information integrated management should take the owner as main integrator and controller. Then, This paper research on the basic conditions for chemical engineering project information integration, Based on this, it build up three layers information integrated management system of large-scale chemical engineering projects based on owner; and analysis and researched the construction and implemented methods of data storage layer 、data managed and shared layer、application layer. Providing a mind of constructive about information integrate management of chemical engineering projects.