The influence of different the depth to the hydrodynamic characteristics of the underwater cylinder vertical launch out of the tube was researched with numerical simulation. The finite volume method based on the multiphase model, continuity equation, transport equations of liquid mass fraction,a dynamic mesh technique and a standard tow-turbulence model are adopted to solve RANS equation in conjunction. The fluid-solid coupling problem of both movement boundary of the cylinder and multiphase flow field was solved by using numerical method. Under the influence of the gravity, the flow field affected the hydrodynamic characteristics of the cylinder was derived with the numerical simulation. Simulation results show that different launch depths affect on the trajectory of underwater cylinder and hydrodynamic. The fluctuation reasons of different pressure drag coefficient, viscous drag resistance coefficient and toll resistance coefficient were derived by analyzing simulation results.