Single or multiple of delaminations have been found frequently on the fracture surface of X70 pipeline steel. In this study, the delamination cracks and their influence on the fracture of pipeline are investigated by both experiment and three-dimensional fracture analyses. It is shown that the three-dimensional stress state is prerequisite for delamination crack and the strength distribution of material influences the form and direction of delamination crack. The delamination cracks are produced on the weak interfaces among the material by the tensile stress perpendicular to them before the fracture passes. The direction of delamination crack depends on the three-dimensional stress fields and strength distribution of material near the crack tip or notch root. The delamination cracks of the fracture through thickness of pipe wall make the effective thickness decrease and the delamination cracks of surface crack are perpendicular to the direction of fracture propagation direction. The delamination cracks reduce the stress triaxiality near crack tip and in turn, improve the fracture toughness of X70 pipeline steel.