The garment materials are one of important factors of affecting thermal comfort of garment. Moisture absorption & quick dry fiber have high-performance of moisture absorption and diffusion. In the paper, the thermal comfort of garment made from moisture absorption & quick dry fiber is studied by wear trial. The subjective and objective methods were used to evaluation thermal comfort of garment. Experiment shown that Experiment shown that moisture absorption & quick dry garment can improve person’s thermal comfort while the microcliamte of garment is small. The moisture absorption & quick dry garment have no obvious advantage to improve thermal comfort of garment while person is static situation or garment size is much big.