In this paper, silk/high-count mixed fabric was explored and developed by product design and performance research. The research showed the arrangement of the proportion of silk and cotton and different fabric weave designs. The data were achieved through the performance tests of all fabrics. And the paper analyzed and studied all the data to find the factors which could effect the characters of the blended fabric. The result showed that The drapability of silk/high count cotton mixed fabric could be closed to that of silk fabric when choosing high count cotton yarn and made pick count under 700 picks/10cm. Fabric anti-pilling tendency will strengthen with the increase of cotton content.