Alginate fibre has attracted great attention in the area of biological medical materials due to its unique biological properties. But its low tenacity greatly hinders its application area. Therefore, the preparation technology of alginate fibre has been as an important research direction in this area in recent years. The purpose of this article is to prepare the calcium alginate fibre with good properties by wet spinning. The structure and properties of this fibre are analyzed by scanning electron microscope，infrared spectrometer，thermal gravimetric analyzer and DSC.