The synthesis of AGE modified polysiloxane was realized by block copolymerization. Using degradation method and different ratio of raw materials, different content of AGE side chains and molecular weight of AGE modified polysiloxanes had been obtained. AGE modified silicone rubber was prepared by Nano-SiO2 and AGE-Modified Polysiloxane Blends. The relationship between the molecular weight of AGE modified polysiloxane, the content of AGE modified side chains and the mechanical properties of AGE modified silicone rubber had been studied. The results showed that AGE modified silicone rubber had better mechanical damping properties than silicone rubber without modification of AGE: lower Tg (-56°C), higher tanδ (0.26), the maximum tensile/rear strengths with appropriate dynamic viscosity (17500mP•s) and the characterization of decreasing tensile/tear strengths with the increasing content of the AGE modified side chains.