This paper presents a modified nonlinear continuum damage model (CDM) applying to analyze compressor blades fatigue developed by Chaboche. The proposed model has been formulated to take into account the effect of different load levels and loading sequence. From a multiaxial fatigue point of view, the mean stress effect has been considered in order to extend the proposed model to multiaxial fatigue conditions. The unsymmetrical cycle fatigue test of TC4 alloy has been carried out to verify the model proposed in this paper and the results show a good agreement to predict fatigue life and damage. Finally, the fatigue life of a compressor blade is predicted using the proposed model under multi-level loading.