Ultrasonic effect is widely applied in biomaterial treatment and this process will happen in ultrasonic reaction kettle of which physical parameters directly affect the treatment effect. This paper introduces a kind of monitored control system of ultrasonic reaction kettle and mainly presents the realization method of key units. Depending on embedded technology, this system includes three layers control unit: ARM central control layer, PC control layer and bottom CAN intelligent node layer which has sensors and actuators. Linux operating system has been transplanted on ARM processor as the software platform. Through the practical hardware arrangement and software design, it can be proved that this system can effectively and accurately monitored control the parameters of ultrasonic reaction kettle.