Paper Title:
Ferrocene-Based Antibacterial Agents: Synthesis, Characterization, and Biological Evaluation of Metal (II) Complexes with Glycine-Derived Compounds
  Abstract

A series of Ferrocene Schiff bases derived from glycine and their cobalt (II), copper (II), nickel (II), and zinc (II) metal complexes have been synthesized and characterized by IR, 1H NMR, MS and elemental analysis, the results conformed well with expected structures. The synthesized ligands, along with their metal (II) complexes, were screened in vitro for their antibacterial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that the metal (II) complexes are more potent in antibacterial activity against one or more species in comparison with those of uncomplexed ligands.

  Info
Periodical
Chapter
Chapter 5: Monitoring and Control of the Manufacturing Process
Edited by
Zhijiu Ai, Xiaodong Zhang, Yun-Hae Kim and Prasad Yarlagadda
Pages
317-320
DOI
10.4028/www.scientific.net/AMR.339.317
Citation
Y. T. Liu, X. M. Sun, D. W. Yin, "Ferrocene-Based Antibacterial Agents: Synthesis, Characterization, and Biological Evaluation of Metal (II) Complexes with Glycine-Derived Compounds", Advanced Materials Research, Vol. 339, pp. 317-320, 2011
Online since
September 2011
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$32.00
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