In this study, we invesgated the mechanical properties of the rabbit femurs fixed with calcium phosphate cement (CPC). Twenty adult rabbits were randomly divided into the control group and the group treated with femur fracture artifically, then fixed with CPC. Two weeks after surgery, all rabbits were sacrificed, and femurs were removed for the three point bending test to examine the changes of mechanical parameters of the femurs. Our results showed that although the maximum tension stress of the femurs in the treatment group was smaller than the control, its crosss-sectional area became bigger, which improved the ablity of the femur to bear more loading with the maximum pressure and absorbed energy during destroy up to 83.5% and 64.3% of normal bone material strength. It indicated that it was practicable to fix the fractured femur with CPC from the biomechanical view piont.