Paper Title:
Application of Two Modeling Methods in Optimization for Adenosine Extraction from Mycelium of Cordyceps Militaris
  Abstract

An experimental mixture design coupled with data analysis by means of both response surface methodology(RSM) and artificial neural network(ANN) was applied to explore the optimum process parameters for adenosine extraction from cultured mycelium of Cordyceps militaris. With the extraction rate of adenosine as index, the critical factors selected for the investigation were extracting temperature, extracting time and solid-liquid radio. The results obtained by the application of ANN were more reliable since better statistical parameters were obtained. The optimum extraction procedure was as follow: extracting time 2.3 h, extracting temperature 48 °C, solid-liquid ratio 1:38 g⋅mL-1. Under the optimal conditions, the corresponding response value predicted for adenosine production was 4.59 mg g-1, which was confirmed by validation experiments.

  Info
Periodical
Advanced Materials Research (Volumes 343-344)
Chapter
Session 3: Biology-Related Materials Research in Environmental Protection
Edited by
David Wang
Pages
826-831
DOI
10.4028/www.scientific.net/AMR.343-344.826
Citation
L. N. Du, J. Song, L. J. Meng, J. H. Lu, Q. F. Meng, L. R. Teng, "Application of Two Modeling Methods in Optimization for Adenosine Extraction from Mycelium of Cordyceps Militaris", Advanced Materials Research, Vols. 343-344, pp. 826-831, 2012
Online since
September 2011
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Price
$32.00
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