Paper Title:
CoMFA Study on Novel Substitute Oxazolidine Derivatives
  Abstract

A series of novel Substitute oxazolidine derivatives with potential herbicide safener activity has been modeled using a 3D quantitative structure-activity relationships approach known comparative molecular field analysis (CoMFA). The cross-validated q2 of CoMFA was 0.612, non-cross-validated R2 was 0.986, and F-test value was 120.1, respectively, with the biological activity of the compounds was expressed by pRC30 (root length). The results are critically discussed using a variety of statistical parameters. The CoMFA model was satisfactory and would be useful for the future design of new N-dichloroacetyl oxazolidine herbicide safener.

  Info
Periodical
Chapter
Chapter 2: Smart Materials for Biomedical Engineering Application
Edited by
J.L. Zhong
Pages
320-325
DOI
10.4028/www.scientific.net/AMR.345.320
Citation
Y. Fu, H. T. Li, Q. S. Zhao, F. Ye, "CoMFA Study on Novel Substitute Oxazolidine Derivatives", Advanced Materials Research, Vol. 345, pp. 320-325, 2012
Online since
September 2011
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Price
$32.00
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