The distributed power generation is an energy development way which can most manifest the multiple advantages such as the energy saving, emission reduction, safety and flexible trait. As a kind of distributed power generation technology of renewable energy, photovoltaic power generation has already transited from supplement energy to alternative energy. Although solar photovoltaic power generation industry develops very quickly in China, actual application cases of substation photovoltaic grid-connected power generation system are few. In this paper, the research of photovoltaic grid-connected power generation system is used in Zhuishan substation in Bengbu Anhui province. The system is the first set of substation photovoltaic-connected grid power generation system in Anhui province. It has being operated for three years safety and steady. The whole application of the system is advanced and groundbreaking in the domestic.