The incorporation of cadmium into clinker during the co-processing of waste with cement kiln was investigated. Cadmium contained reagent was added to the cement raw meal to produce clinkers after clinkerization process. XRD analysis and SEM-EDS analysis were employed to indentify the major mineral phase of clinker and the cadmium contained mineral phase. Leaching test, sequential extraction procedures were employed to evaluate the leaching potential of cadmium in clinker. The results show the stabilization rate of cadmium during the clinkerization process is low. The incorporation ratio of cadmium in C2S is 0.32%~1.14%, the incorporation ability of cadmium in C2S is higher than C3S. The major mineral phases of clinker with the incorporation of cadmium were CH, C3S and C2S. The average leaching concentration of cadmium of clinker was 1.4 μg/L, which was higher than the blank samples. BCR Sequential extraction procedures analysis of the clinkers show exchangeable, water and acid-soluble fraction and residual fraction were very small, while the reducible phase of cadmium was up to 95.13%.