Forecast about nutrient (mainly referring to nitrogen, N and phosphorus, P) emission from point sources of Gan River was made on the base of pollution state and spatial-temporal variety regularity from 1999 to 2009. During the research period, maximum of total nutrient emission was in Ganzhou (TN 1.64×104t, TP 0.21×104t), which is followed by Nanchang. Just in terms of 2009, total nutrient emissions from Ganzhou and Nanchang account for 60% and Nanchang, as a main control station, per capita nutrient emissions increased at the speed of 7.96% and 7.17% in 2008 and 2009, respectively. According to the prediction model, TN and TP emissions from Gan River basin will be 5.25×104t and 0.68×104t, respectively. Meanwhile, point sources still is the principal part of total nutrient emission from Gan River, which will have a negative impact on water quality of estuary and Poyang Lake. Therefore, the key to comprehensive management of water pollution is point sources.