This paper presents a study on the fatigue performance of a new type solid round rigid suspender in a high-speed railway bridge. The relevant information about the model design, manufacture, loading procedure and test scheme is presented. The model test results show that the maximum axial stress amplitude are less than the allowable fatigue stress amplitude for most of the measuring points, and no crack occurs on the short and the long suspender models’ body and connection structural detail after 2 million fatigue cycles, the fatigue performance meets the requirement. The bearing capacity test results after fatigue test show that the short and the long suspender models entering plastic state and without fracture under 131% and 119% of the test load. The suspenders’ bearing capacity meets the design requirement. This fatigue model test study shows that the design of the new type solid round rigid suspender is reasonable and safe.