The purpose of this paper is to find the pollution diffusion regularity near sewage outlet area of Yuncheng reach of the Fen River. A 2-D water hydrodynamic and quality model was used to simulate flow field, the water quality and contamination dispersion. The parameters of the model were calibrated with measured data of the water depth, flow and water quality in Yuncheng reach of the Fen River. According to the simulated result, the total area of pollution belt with 19 sewage outlets is 8.89km2 in normal year. And 3.89% of the reach has a worse water quality than V class in standard. The percentage of V and Ⅳ Class of water is 69.17% and 26.94%.In dry year, the total area of pollution belt with 19 sewage outlets is 8.89km2.The percentage of inferior V, V and Ⅳ Class of water is 27.80%, 69.46% and 2.74%. It was shown by the simulated results that the concentration gradient decreases with increasing distance to the outlets and the dilution and dispersion of pollutants was enhanced by a greater river flow.