A vibration reducing system of seismic isolation bearings is introduced into beam string structures. The vibration control on seismic response of beam string structures (BSS) with seismic isolation bearings is discussed. Firstly finite element models for different analyses are established by using explicit dynamic analysis program LS-DYNA. Then the seismic response analyses are performed on a single beam string structure with and without seismic isolation bearings to investigate the effectiveness of the seismic isolation bearings in reducing vibration response of BSS. Furthermore, parametric analyses are conducted to examine the effects of lateral stiffness and damping of the seismic isolation bearings on seismic isolation. The analytical results indicate that the vibration reducing system can effectively reduce the vibration response of BSS against seismic force, and be applied in the vibration control of BSS.