For the large centrifugal fan impeller, its working condition generally is bad, and its geometry generally is complex. So its displacements and stresses distribution are also complex. In this paper, we can obtain the fan impeller’s displacements and stresses distribution accurately through numerical simulation in G4-73 type centrifugal fan impeller using the finite element method software ANSYS. The calculation result shows that the maximum total displacement of the impeller is m, it occurs on the position of the half of the blade near the outlet of the impeller; and the maximum equivalent stress of the impeller is 193 MPa, it occurs on the contacted position of the blade and the shroud near inlet of the impeller. Furthermore, check the impeller strength, the result shows that the strength of the impeller can meet the requirement.