Fabrication and Properties of Hydroxyapatite-Ti Network Composites |
| Journal |
Advanced Materials Research (Volumes 41 - 42) |
| Volume |
Structural Integrity and Failure |
| Edited by |
Xiaozhi Hu, Brent Fillery, Tarek Qasim and Kai Duan |
| Pages |
41-48 |
| DOI |
10.4028/www.scientific.net/AMR.41-42.41 |
| Online since |
April, 2008 |
| Authors |
Zhi Meng Xiu,
Yi Liu,
Ji Guang Li,
Di Huo,
Xiao Dong Li,
Xu Dong Sun,
Kai Duan,
Xiao Zhi Hu
|
| Keywords |
Biocomposite, Cytotoxic Test, Hemolysis Test, Hydroxyapatite (HA), Mechanical Property, Titanium (Ti) |
| Abstract |
Hydroxyapatite (HA) powder was synthesized by a sol-gel method with Ca(OH)2 and
H3PO4 as reactants. The HA granules were then coated with TiH2 powder using a mechanical
mixing method. The HA-TiH2 material system produced HA-Ti composites after hot-pressing at
1050ºC. The HA-Ti composites are mainly composed of HA and Ti, with small amounts of Ca2P2O7
and Ca3(PO4)2 phases. Fracture toughness and bending strength are 2.4 MPa·m1/2 and 54.3 MPa,
respectively for the HA-20vol%Ti composite, higher than those of the pure HA ceramic. The
improvement in properties is because of the unique 3D network structure of Ti, which is an ideal
reinforcement structure for the weak and brittle HA. According to ISO/TR 7405-1984, hemolysis
test was performed to evaluate the blood compatibility of the material. The results show that the
hemolysis rate of the HA-20vol%Ti composite is 0.56%. Relative growth rates (RGR) of L-929
cells soaked after 6 days in the HA-20vol%Ti group, pure Ti group, black group and pure Pb group
were 132%, 100%, 90% and 6% respectively, while the level of cytotoxicity was grade 0 in HA-Ti
composite group. These results imply that the HA-20vol%Ti composite has good biocompatibility
and bioactivity. |
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