Paper Title:
Effects of Vision Clues on Spatial Cognition of Mice
  Abstract

To investigate the effect of vision clues on spatial cognitive ability of mice, 20 healthy Mus musculus (Km) mice were divided into two groups, control group and test group. During the experiment, the control group was trained in the Morris water maze with the visual signals while all the visual reference objects of Morris water maze were removed when the test group was trained. The latencies and swimming paths of the two groups were recorded for comparing the effect of vision clues on spatial cognitive ability of the mice. The results showed that there was no significant difference of swimming speed between the two groups, but both the latencies to find the hidden platform and swimming paths of the test group increased notably compared with the control group during the place navigation testing and probe trial testing (P<0.05). According to these results, we concluded that vision clues played a critical role on the spatial cognition ability of mice. If the visual reference objects of Morris water maze were removed, the spatial cognitive ability of the mice would decrease, the latencies increased significantly and swimming paths became long and disorder.

  Info
Periodical
Chapter
Chapter 2: Signal and Image Processing in Industry
Edited by
Gary Yang
Pages
303-307
DOI
10.4028/www.scientific.net/AMR.429.303
Citation
Z. Zhou, J. L. Chang, M. Xie, X. M. Liao, "Effects of Vision Clues on Spatial Cognition of Mice", Advanced Materials Research, Vol. 429, pp. 303-307, 2012
Online since
January 2012
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xiao Dong Huang, Jian Ying, Yan Chun Wang, Kuang Ren
Chapter 5: Biological Materials and Technologies
Abstract:Objective: To investigate anti-aging effects of deoxyschizandrin in rats and its mechanisms. Methods: D-galactose (120mg • kg-1 • d-1) was...
373
Authors: Wei Jing Sun, Shu Jing, Chun Mei Wang, Cheng Yi Zhang, Hong Xia Sun, Jia Hong Li, Jing Hui Sun, Jian Guang Chen, He Li
Chapter 17: Agricultural Products Processing and Biological Pharmaceutical
Abstract:This study focused on the improvement of Schisandra polysaccharide on the learning and memory in D-galactose-induced brain aging mice, to lay...
1595