Paper Title:
Construction of Nonbiofouling Biofunctional Glass Surface by Self-Assembled Monolayer and Graft Hydrophilic Polymer
  Abstract

This paper introduces a new method of surface modification by self-assembled monolayer (SAM) and polymer monolayer grafting. Since most of the glass surfaces lack the reactive functional group, an activation process with 3-(trimethoxysilyl)propyl methacrylate(TPM) is used in our experiment to generate the vinyl reactive sites on the substrate surface for further graft polymerization. The TPM saline layer acts as the “anchor” part to link the functional part onto the surface of substrate. The paper summarizes the surface modifications by the polymerizations of PEGMA, AA(Acrylic acid) and NVP(Nitrogen-vinyl-2-pyrrolidone) respectively and their applications for protein adsorption and cell adhesion through a series of measurements. In previous research, AA and NVP had also been adopted for surface treatment and had achieved good results. The substrate can be glass, alumina, silicon, metals or stainless steel. We choose glass as our substrate during the experiment.

  Info
Periodical
Advanced Materials Research (Volumes 47-50)
Edited by
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam
Pages
1343-1346
DOI
10.4028/www.scientific.net/AMR.47-50.1343
Citation
Z. B. Liu, B. Zhang, B. Y. F. Pow, M. Yang, A. F. T. Mak, "Construction of Nonbiofouling Biofunctional Glass Surface by Self-Assembled Monolayer and Graft Hydrophilic Polymer", Advanced Materials Research, Vols. 47-50, pp. 1343-1346, 2008
Online since
June 2008
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Price
$32.00
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