Electrospinning Nanocomposite Nanofibers of Hydroxyapatite/Chitosan |
| Journal |
Advanced Materials Research (Volumes 47 - 50) |
| Volume |
Multi-functional Materials and Structures |
| Edited by |
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam |
| Pages |
1363-1366 |
| DOI |
10.4028/www.scientific.net/AMR.47-50.1363 |
| Online since |
June, 2008 |
| Authors |
Y.Z. Zhang,
B. Su,
Chwee Teck Lim
|
| Keywords |
Bone Tissue Engineering, Chitosan, Electrospinning, Hydroxyapatite (HA), Nanocomposite |
| Abstract |
This paper presents a two-step approach for electrospinning of hydroxyapatite/chitosan
(HAp/CTS) nanocomposite, which was firstly prepared by an in situ co-precipitation method.
Continuous HAp/CTS nanofibers with diameters of 214 ± 25 nm were produced successfully with
the aid of an ultrahigh molecular weight poly(ethylene oxide) (UHMWPEO). The HAp
nanoparticles with aggregations to some extent were incorporated along the electrospun CTS-based
nanofibers. And their crystallite structure can be preserved to some extent although an acidic solvent
system was used. Current nanocomposite nanofibers of HAp/CTS may be of potential interest for
bone repair and regeneration application. |
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