Paper Title:
Investigation of Platelet Adhesion Behavior on Si-N-O Films Synthesized by Unbalanced Magnetron Sputtering
  Abstract

Si-N-O films have drawn researcher’s much attention recently due to their potential superiority in blood compatibility of biomaterials. In this paper, Si-N-O films were synthesized on <100> silicon substrates by pulsed reactive unbalanced magnetron sputtering a single crystal silicon target with high purity in a mixture atmosphere of Ar and N2. XPS and FTIR results showed the Si-N-O films synthesized at higher N2 flux could be described to random bonding model (RBM). In RBM, the Si2p existed in the form of a-Si3N4 and SiNνO4-ν (ν=0,1,2,3,4) components. Platelet adhesion behavior on Si-N-O films was assessed by platelet adhesion test and Lactate dehydrogenase (LDH) assay, qualitatively and quantitatively separately. The correlativity of film chemical structure and blood compatibility was investigated. The results of platelet adhesion and activation showed that the RBM film with higher N/O ratio exhibited favorable blood compatibility. It was shown that the Si-N-O film with specific composition and chemical bonding state was superior in blood compatibility compared to low temperature isotropic carbon (LTIC).

  Info
Periodical
Advanced Materials Research (Volumes 47-50)
Edited by
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam
Pages
1407-1410
DOI
10.4028/www.scientific.net/AMR.47-50.1407
Citation
Z. Y. Shao, P. Yang, Y. X. Leng, Q. Zhang, G. J. Wan, H. Sun, G. J. Cai, N. Huang, "Investigation of Platelet Adhesion Behavior on Si-N-O Films Synthesized by Unbalanced Magnetron Sputtering", Advanced Materials Research, Vols. 47-50, pp. 1407-1410, 2008
Online since
June 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Fei Xiong Mao, Tao Liu, Shi Wei Liu, Jing Kun Yu
Chapter 16: Sustainable Manufacturing Technologies
Abstract:Mg films were prepared by magnetron sputtering on zirconia substrate. The surface morphology, structure and adhesion performance were...
2834
Authors: Tanakorn Khumtong, Rachsak Sakdanuphab
Chapter 7: Coatings and Surface Engineering
Abstract:In this work, titaniumoxynitride (TiOxNy) thin films were deposited on glass slide substrates by using reactive dc...
540