Paper Title:
In Vitro Biocompatibility Study of Nano TiO2 Materials
  Abstract

Nano TiO2 material is an extensively used and adequately studied material and has a close contact with human in various fields, such as dope, dye, ceramic, cosmetic and medicine. Therefore, it’s very important to study the biocompatibility and biosafety of nano TiO2 materials. In the present study, various nano TiO2 materials with different dimension and crystal structures were confected to suspensions with varied concentrations and evaluated in cell model (mouse fibrocyte) after autoclaving sterilization. After 24h, 48h and 72h of cell culture experiments, MTT assay was used to examine the cell proliferation behavior and the flow cytometry was used to examine the cell apoptosis behavior. The present results of cell experiment showed that nano TiO2 materials had no effect on cell proliferation and apoptosis in a certain range of time and concentration. MTT assay indicated the relative cell proliferation rate in all nano TiO2 material groups were above 92% and the toxicity grade were 0 or 1 class.

  Info
Periodical
Advanced Materials Research (Volumes 47-50)
Edited by
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam
Pages
1438-1441
DOI
10.4028/www.scientific.net/AMR.47-50.1438
Citation
W. Han, Y. D. Wang, Y.F. Zheng, "In Vitro Biocompatibility Study of Nano TiO2 Materials", Advanced Materials Research, Vols. 47-50, pp. 1438-1441, 2008
Online since
June 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xiao Bing Zhao, Xuan Yong Liu, Chuan Xian Ding
Abstract:Nanostructured titania coatings were prepared by atmospheric plasma spraying using commercial nano-powder. The effects of plasma forming gas...
73
Authors: Ming Kwei Lee, Tsung Hsiang Shih, Chung Min Shih
Abstract:Nano-scaled particle of anatase phase titanium oxide was obtained from the conversion of ammonium oxotrifluorotitanate by thermal treatment...
2008
Authors: Xi Xin Wang, Jian Ling Zhao, Zhao Hui Meng, Jia Wei Yan
Abstract:Titania nanoparticles were successfully synthesized through an easily controlled and simple autothermal gelation process. Effects of H2O2...
1188
Authors: Yun Lu, Hiroyuki Yoshida, Hiroyuki Nakayama, Liang Hao, Mitsuji Hirohashi
Abstract:In the present work, 2-step mechanical coating technique (2-step MCT), an advanced MCT, was proposed and carried out to form TiO2/Ti...
1229
Authors: Shahab Khameneh Asl, M. Kianpour Rad, Sayed Khatiboleslam Sadrnezhaad, Mohammad Reza Vaezi
Abstract:Titanium dioxide is a cheap, chemically stable and non-toxic material. However its photocatalytic properties are unstable and it is a modest...
1340