Paper Title:
Preparation and Characterization of Poly(D,L-Lactide) and Silk Fibroin Nanocomposite Microparticles for Potential Use in Tissue Engineering
  Abstract

Nanocomposite poly(D,L-lactide) (PDLL)-based microparticles containing silk fibroin (SF) nanoparticles were prepared by oil-in-water emulsification solvent evaporation technique of PDLL/SF nanocomposite. The PDLL/SF nanocomposite was obtained from nanoprecipitating SF into PDLL solution in acetone before dried in vacuum oven. The nanocomposite microparticles with PDLL/SF ratios of 20/1, 10/1 and 5/1 (w/w) were prepared and investigated. Interactions between PDLL and SF of microparticles can be observed from FT-IR and thermogravimetric results. Sizes of the SF nanoparticles and the nanocomposite microparticles from SEM micrographs were in the ranges of 50-500 nm and 50-200 µm, respectively. The sizes of SF nanoparticles and nanocomposite microparticles increased as increasing the SF ratio. Surface roughness of the resulted microparticles also increased with the SF ratio.

  Info
Periodical
Advanced Materials Research (Volumes 55-57)
Main Theme
Edited by
Tawee Tunkasiri
Pages
725-728
DOI
10.4028/www.scientific.net/AMR.55-57.725
Citation
N. Kotsaeng, Y. Srisuwan, Y. Baimark, N. Narkkong, W. Simchuer, "Preparation and Characterization of Poly(D,L-Lactide) and Silk Fibroin Nanocomposite Microparticles for Potential Use in Tissue Engineering", Advanced Materials Research, Vols. 55-57, pp. 725-728, 2008
Online since
August 2008
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$32.00
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