Paper Title:
Prediction of FNR Regulated Genes and Metabolic Pathways Potentially Involved in Anaerobic Growth of Acidithiobacillus Ferrooxidans
  Abstract

Efficient bioleaching requires adequate access to oxygen to drive the biochemical reactions that underpin iron and sulfur oxidation and ultimately copper solubilization. However, microaerophilic or anaerobic conditions may occur in certain parts of the heap, especially in areas of intense microbial activity or in biofilms where oxygen gradients occur. Microaerophilic conditions have also been detected in pristine acidic environments and in abandoned bioleaching operations. An important microorganism in bioleaching at ambient temperatures is the chemolithoautotrophic bacterium Acidithiobacillus ferrooxidans. In addition to its well established role in oxidative processes, it has been shown to be capable of reducing metals such as iron and sulfur, and the products of these reactions may promote passivation of mineral surfaces and impede efficient solubilization of copper. In an effort to advance our understanding of the genetic and physiological basis of anaerobic metabolism, gene clusters controlled by the master anaerobic transcriptional regulator FNR were predicted in the genome of A. ferrooxidans using bioinformatics techniques. These clusters were found to be associated with energy metabolism, nitrogen fixation and carbohydrate metabolism. The results not only support previous evidence for proposed anaerobic metabolic pathways but also identify new genetic components and pathways that may be important for anaerobic or microaerophilic growth of this microorganism.

  Info
Periodical
Advanced Materials Research (Volumes 71-73)
Edited by
Edgardo R. Donati, Marisa R. Viera, Eduardo L. Tavani, María A. Giaveno, Teresa L. Lavalle, Patricia A. Chiacchiarini
Pages
195-198
DOI
10.4028/www.scientific.net/AMR.71-73.195
Citation
H. Osorio, J. P. Cárdenas, J. H. Valdés, D. S. Holmes, "Prediction of FNR Regulated Genes and Metabolic Pathways Potentially Involved in Anaerobic Growth of Acidithiobacillus Ferrooxidans", Advanced Materials Research, Vols. 71-73, pp. 195-198, 2009
Online since
May 2009
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: John D. Albino, Indumathi M. Nambi
Abstract:In-situ applications such as Microbial Enhanced Oil Recovery (MEOR) and remediation of contaminated sites demand production of biosurfactants...
623
Authors: Jun Li, Zhi Yu Zhang, Qiang Liu, Qing Yuan Yang
Abstract:The simultaneous removal of carbon and nitrogen of the anaerobically pretreated distillery wastewater with nitrate, nitrite and ammonia...
2939
Authors: Jin Xiang Fu, Xi Jiang, Jun Zhao
Chapter 13: Material Processing Technology
Abstract:Through running anaerobic ammonia oxidation reactors for a few days, we found that inorganic carbon source has great influence on anaerobic...
2226
Authors: Dong Xing, Yong Feng Li, Li Wei, Jing Wei Zhang
Chapter 1: Environmental Materials, Chemistry, Biology Technology and Processes
Abstract:Most Oilfield of China has been a stage of Oil recovery with high water, microbial residual oil gasification technology as the oilfield's...
21