Three FRP fishing vessel hulls with different knuckles, the two knuckles ship, the round bilge ship and the single knuckle ship (hereinafter using abbreviation the TKS, the RBS, and the SKS, respectively), are studied to reduce resistance and enhance strength. Here the TKS is a variation design from the RBS. And the knuckles on the hull were designed paralleled with the streamlines of the hull surface of the RBS at the design speed, and the SKS is applied as the comparison ship. The resistance of the three hulls is predicted using the CFD software FLOW-3D, at the same time, the midship section modulus of the three hulls is calculated in this paper. It shows that the resistance of the TKS is slightly lower than that of the RBS at the design speed, and about 50% lower than that of the SKS. On the other side, the strength of the TKS increased about 15% than the RBS, and 6.9% than the SKS.